Membrane Receptor Signaling in Health and Disease

نویسندگان

  • ALFREDO ULLOA-AGUIRRE
  • GUADALUPE MAYA-NÚÑEZ
  • CARLOS TIMOSSI
چکیده

Morgan, P. J., Nanoff, C., Strosberg, A. D., and Jockers, R. (1999). Dual signaling of human Mel1a melatonin receptors via G(i2), G(i3), and G(q/11) proteins. Mol. Endocrinol. 13, 2025–2038. Ersahin, C., Masana, M. I., and Dubocovich, M. L. (2002). Constitutively active melatonin MT1 receptors in male rat caudal arteries. Eur. J. Pharmacol. 439, 171–172. Hunt, A. E., Al-Ghoul, W. M., Gillette, M. U., and Dubocovich, M. L. (2001). Activation of MT(2) melatonin receptors in rat suprachiasmatic nucleus phase advances the circadian clock. Am. J. Physiol. Cell Physiol. 280, C110–C118. Klein, D. C., Coon, S. L., Roseboom, P. H., Weller, J. L., Bernard, M., Gastel, J. A., Zatz, M., Iuvone, P. M., Rodriguez, I. R., Begay, V., Falcon, J., Cahill, G. M., Cassone, V. M., and Baler, R. (1997). The melatonin rhythm-generating enzyme: Molecular regulation of serotonin N-acetyltransferase in the pineal gland. Recent Prog. Horm. Res. 52, 307–357. Krauchi, K., Cajochen, C., Werth, E., and Wirz-Justice, A. (2000). Functional link between distal vasodilation and sleep-onset latency? Am. J. Physiol. Regul. Integr. Comp. Physiol. 278, R741–R748. Krause, D. N., Geary, G. G., Doolen, S., and Duckles, S. P. (1999). Melatonin and cardiovascular function. Adv. Exp. Med. Biol. 460, 299–310. Liu, C., Weaver, D. R., Jin, X., Shearman, L. P., Pieschl, R. L., Gribkoff, V. K., and Reppert, S. M. (1997). Molecular dissection of two distinct actions of melatonin on the suprachiasmatic circadian clock. Neuron 19, 91–102. Lotufo, C. M., Lopes, C., Dubocovich, M. L., Farsky, S. H., and Markus, R. P. (2001). Melatonin and N-acetylserotonin inhibit leukocyte rolling and adhesion to rat microcirculation. Eur. J. Pharmacol. 430, 351–357. Malpaux, B., Migaud, M., Tricoire, H., and Chemineau, P. (2001). Biology of mammalian photoperiodism and the critical role of the pineal gland and melatonin. J. Biol. Rhyth. 16, 336–347. Masana, M. I., Doolen, S., Ersahin, C., Al-Ghoul, W. M., Duckles, S. P., Dubocovich, M. L., and Krause, D. M. (2002). MT2 Melatonin receptors are present and functional in rat caudal artery. J. Pharmacol. Exp. Ther. 302, 1295–1302. Reppert, S. M., Weaver, D. R., and Godson, C. (1996). Melatonin receptors step into the light: Cloning and classification of subtypes. Trends Pharmacol. Sci. 17, 100–102. Vanecek, J. (1998). Cellular mechanisms of melatonin action. Physiol. Rev. 78, 687–721. von Gall, C., Garabette, M. L., Kell, C. A., Frenzel, S., Dehghani, F., Schumm-Draeger, P. M., Weaver, D. R., Korf, H. W., Hastings, M. H., and Stehle, J. H. (2002). Rhythmic gene expression in pituitary depends on heterologous sensitization by the neurohormone melatonin. Nat. Neurosci. 5, 234–238. Wehr, T. A. (2001). Photoperiodism in humans and other primates: Evidence and implications. J. Biol. Rhyth. 16, 348–364. Witt-Enderby, P. A., and Li, P. K. (2000). Melatonin receptors and ligands. Vitam. Horm. 58, 321–354.

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تاریخ انتشار 2010